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ForumsCardiovascular OutcomesSOUL trial preliminary data — November 2025 Page 3

SOUL trial preliminary data — November 2025

JenMemphis Sun, Mar 16, 2025 at 2:50 AM 51 replies 2,130 viewsPage 3 of 11
COA_Karl
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Mar 18, 2025 at 3:05 PM#11
Dr.LeslieOBGYN said:
Bayesian meta-analysis perspective on the trial evidence: traditional frequentist meta-analyses report point estimates and confidence intervals.

No disagreement, though it depends on where somebody is starting from, and this thread has been assuming a starting point nobody stated.

23 21matt_MKE, Dr.ReproEndo, lucas_SP_BR and 20 others
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sarah_nash92
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Mar 18, 2025 at 8:58 PM#12
MikeKY_noInsulin said:
InsuranceTom said: ...regarding the trial evidence...

Thank you for spelling out the reasoning rather than just the conclusion.

Last edited: Mar 19, 2025 at 2:58 AM
24 22JakeSmashed95, NauseaFreeNow, SteveThurs and 21 others
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Dr.PeteFamMed
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Mar 19, 2025 at 2:51 AM#13
Dr.LeslieOBGYN said:
Bayesian meta-analysis perspective on the trial evidence: traditional frequentist meta-analyses report point estimates and confidence intervals.

Worth saying that the confident version of this is more useful to the person writing it than to the person reading it.

25 23LindaRN_retired, tommy_boulder, hyun_seoul and 22 others
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SleepDoc_PDX
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Mar 19, 2025 at 8:44 AM#14

The figures, for anyone assembling their own picture. If you are going to change something, change one thing and give it long enough to express itself. Four weeks is the usual minimum for anything pharmacological on this board, and two weeks of data has told you almost nothing.

26 24sophie_paris, mel_PDX, Dr.AddMedPHL and 23 others
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Admin
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Mar 19, 2025 at 2:37 PM#15

Moderator note: two posts asking for a source have been merged into one. Please search the thread before asking again.

27 0PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 24 others
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