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Evidence-based GLP-1 & peptide discussion since 2023
ForumsCardiovascular OutcomesHas anyone dealt with glp-1 and peripheral arterial disease? Page 4

Has anyone dealt with glp-1 and peripheral arterial disease?

traveltech_sara Fri, Jan 31, 2025 at 6:48 PM 24 replies 2,011 viewsPage 4 of 5
PedsEndoPhilly
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Feb 5, 2025 at 2:29 AM#16

Adding the clinical framing, because it changes how the question reads.

Senior perspective on cardiovascular risk: I'm 62 years old and started this journey skeptically. My cardiologist recommended it after years of failed interventions.

10 months later: down 45 lbs, more mobile, pain reduced, medications simplified. My quality of life has improved dramatically. I wish this existed 20 years ago.

To other older adults hesitating: the SELECT trial proved benefit in our age group. You deserve to feel good in your body regardless of age.

45 18sarah_TO, wendy_avl, jason_paloalto and 42 others
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TrialTracker_MD
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Feb 5, 2025 at 5:29 PM#17
LabKate said:
traveltech_sara said: ...cardiovascular risk is just another fad...

This answered a question I did not know how to ask. Taking it to my next appointment.

46 19stefan_berlin, Dr.EM_Chicago, pete_RVA and 43 others
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Dr.GutHealth
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Feb 6, 2025 at 8:29 AM#18

Adding the clinical framing, because it changes how the question reads.

Positive "side effect" of cardiovascular risk: my blood pressure dropped so much that I'm now off losartan entirely! My cardiologist is thrilled.

If you're on BP meds and losing weight on a GLP-1, monitor your BP at home regularly. Hypotension symptoms (dizziness, lightheadedness when standing) mean your BP meds may need reduction. Don't wait for your next scheduled appointment — call your doctor.

47 20jennifer_SEA, tyler_CSCS, VanRx_Mike and 44 others
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bbq_ray_KC
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Feb 6, 2025 at 11:30 PM#19
Dr.GutHealth said:
Positive "side effect" of cardiovascular risk: my blood pressure dropped so much that I'm now off losartan entirely!

Second this. The detail I would add is minor and it is already implied above.

48 21WendyG_ATL, SaraMom3, Dr.MetabolicMD and 45 others
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mike_mod
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Feb 7, 2025 at 2:31 PM#20

Moderator note: good thread. Keeping it here rather than moving it, because the question is general enough to be useful. Report rather than reply if it drifts again.

20 18PurityPaulOR, MaxMetOK, MounjBrad and 17 others
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