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ForumsRetatrutide & Triple AgonistsWill reta make sema and tirz obsolete? Page 3

Will reta make sema and tirz obsolete?

andrew_nyc Sun, Apr 5, 2026 at 9:23 AM 33 replies 1,028 viewsPage 3 of 7
Dr.BariatricHTX
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Apr 6, 2026 at 1:55 PM#11
pat_auckland said:
It helps to say which part of this you are uncertain about.

That holds where the measurement is reliable. Where it is noisy — and a lot of what gets tracked here is noisy — the same reasoning produces confident nonsense.

7 5CarlaRPh_TPA, steph_laguna, fiona_glasgow and 4 others
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B12Beth
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Apr 7, 2026 at 11:14 AM#12
Dr.SportsMedIN said:
The glucagon component looks paradoxical and is not.

That reframing is the part I needed. Sending this to two other people who asked me the same thing last week.

Last edited: Apr 7, 2026 at 2:14 PM
8 6carl_compliance, DanielChem_CHI, marco_milano and 5 others
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BiostatsBrad
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Apr 8, 2026 at 8:32 AM#13
pat_auckland said:
It helps to say which part of this you are uncertain about.

Filing a mild objection. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit. Pushing back on the consensus forming here. Consistency is not the same as correctness, and a board that agrees with itself quickly is usually agreeing with the first person who sounded certain.

9 7FranDenver, Dr.BariatricHTX, LindaRN_retired and 6 others
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HPLC_Greg
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Apr 9, 2026 at 5:50 AM#14

One concrete data point for the thread. For anyone reading later: the numbers in this thread are worth checking against a primary source before you act on them, including mine. Half the figures circulating in this community trace back to a secondary summary that dropped a qualifier.

10 8Dr.MetabolicMD, RetaRick_CA, JenPlateau and 7 others
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mike_mod
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Apr 10, 2026 at 3:08 AM#15

Moderator note: reminder that nothing in this thread is medical advice, and that clinical claims need a source. Thread quality here is what the rules are for. Keep it up.

11 9PurityPaulOR, MaxMetOK, MounjBrad and 8 others
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