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Evidence-based GLP-1 & peptide discussion since 2023
ForumsLab Results & BiomarkersOptimal lab testing frequency on GLP-1 — looking for input Page 2

Optimal lab testing frequency on GLP-1 — looking for input

MikeNYC_runner Mon, Dec 22, 2025 at 1:23 AM 15 replies 1,091 viewsPage 2 of 3
Dr.NateNeph
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Dec 22, 2025 at 3:18 AM#6
labquiet_amy said:
A defensible baseline is short: HbA1c and fasting glucose, a lipid panel with ApoB if you can get it, ALT and AST, creatinine with eGFR, TSH, ferritin…

Filing a mild objection. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit. I would drop the "get everything" instinct further than this thread does. Every extra test is another chance at a false positive, and incidental findings have their own cost in scans, biopsies and worry.

Last edited: Dec 22, 2025 at 5:18 AM
12 7JakeSmashed95, NauseaFreeNow, SteveThurs and 9 others
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jason_paloalto
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Dec 22, 2025 at 4:02 AM#7
MikeNYC_runner said:
My prescriber ordered three tests and this board recommends about twenty, and I would like to know which of those two lists is right.

PSA: get baseline labs BEFORE starting baseline bloodwork therapy. You need a "before" picture to measure progress. My recommended pre-treatment panel:

  1. CMP + A1C + fasting insulin
  2. Complete lipid panel with particle count if possible
  3. hsCRP, ferritin, B12, vitamin D
  4. Thyroid panel (TSH + free T4)
  5. CBC with differential
  6. Liver panel (ALT, AST, GGT)
  7. DEXA scan or body composition

Total cost at Quest without insurance: ~$200. Worth every penny for the data.

Last edited: Dec 22, 2025 at 9:02 AM
11 6Dr.PathRoch, mona_PHX, andrew_nyc and 8 others
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hans_munich
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Dec 22, 2025 at 4:46 AM#8
Dr.NateNeph said:
I would drop the "get everything" instinct further than this thread does.

Blood work came back perfect. baseline bloodwork + this community = winning. 🏆

Last edited: Dec 22, 2025 at 10:46 AM
10 5Dr.LipidDallas, alex_tucson, kevin_tulsa and 7 others
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carlos_SATX
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Dec 22, 2025 at 5:30 AM#9

Following on from JakeSmashed95 — and this may be the naive question:

How often to repeat it, because quarterly seems to be the convention and I cannot find the reasoning?

9 4LindaRN_retired, tommy_boulder, hyun_seoul and 6 others
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MikeNYC_runner
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Dec 22, 2025 at 9:03 AM#10

Reporting back.

Took the whole panel in rather than the one flagged line, and the conversation lasted two minutes instead of generating three more tests.

49 22MASHdoc_SA, GenomicsKate, Dr.ObesityMed and 46 others
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