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Evidence-based GLP-1 & peptide discussion since 2023
ForumsLab Results & BiomarkersLiver enzymes trending down on GLP-1 — what worked for you? Page 3

Liver enzymes trending down on GLP-1 — what worked for you?

SallyK_inj Tue, Nov 25, 2025 at 3:31 AM 12 replies 1,209 viewsPage 3 of 3
TrialTracker_MD
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Nov 29, 2025 at 11:21 PM#11
Dr.EM_Chicago said:
Worth answering the question that was asked rather than the one behind it.

True, with the qualification that this is a self-selected group. The people for whom it did not work post less, and that shapes everything we think we know.

17 15Dr.EM_Chicago, pete_RVA, CarlaRPh_TPA and 14 others
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TomFromTexas
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Nov 30, 2025 at 3:39 AM#12
james_edin said:
Liver enzyme update related to liver and MASH: I had mildly elevated ALT/AST at baseline (likely NAFLD).

Bookmarking. The distinction being drawn above is the one nobody else makes.

18 16Dr.NateNeph, PharmD_Rodriguez, julia.endo and 15 others
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kate.chem
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Nov 30, 2025 at 7:57 AM#13
Dr.EM_Chicago said:
Worth answering the question that was asked rather than the one behind it.

Pushing back on Dr.EM_Chicago here. Filing an objection on the n=1 problem. Personal experience is genuine evidence about one person and very weak evidence about anybody else, and this thread keeps promoting the first into the second.

19 17tyler_CSCS, VanRx_Mike, steve_okc and 16 others
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FDA_TrackerJim
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Nov 30, 2025 at 12:15 PM#14

One concrete data point for the thread. The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the same conditions. Nobody wants that answer and it is still the answer.

Last edited: Nov 30, 2025 at 3:15 PM
20 18Dr.LeslieOBGYN, MikeNYC_runner and 17 others
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mike_mod
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Nov 30, 2025 at 4:33 PM#15

Moderator note: a couple of off-topic posts removed.

21 19PurityPaulOR, MaxMetOK, MounjBrad and 18 others
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