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Evidence-based GLP-1 & peptide discussion since 2023
ForumsRetatrutide & Triple AgonistsTRIUMPH-2 obesity without diabetes — anyone have experience? Page 2

TRIUMPH-2 obesity without diabetes — anyone have experience?

Dr.ObesityLA Wed, Apr 16, 2025 at 8:08 AM 23 replies 1,941 viewsPage 2 of 5
jason_paloalto
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Apr 17, 2025 at 8:37 PM#6

Adding the numbers, since they settle part of this. One habit that pays for itself: post the method alongside the number. A figure without its method cannot be checked, and an unchecked figure is how this community accumulates folklore.

10 5tane_welly, Dr.PathRoch, mona_PHX and 7 others
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pam_columbus
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Apr 18, 2025 at 11:13 AM#7

One thing that is still open after LindaRN_retired’s answer:

Why adding glucagon agonism to an anti-obesity drug is not self-defeating, given that glucagon raises blood glucose?

9 4alex_tucson, kevin_tulsa, Dr.PainCLE and 6 others
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Dr.NateNeph
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Apr 19, 2025 at 1:49 AM#8
jason_paloalto said:
One habit that pays for itself: post the method alongside the number.

There is a second half to this that has not been said yet. The distinction that resolves most of these threads is between what is true on average and what is true for one person. Both are real; they answer different questions and get quoted as if they were the same one.

8 3SteveThurs, B12Beth, RickReta_CO and 5 others
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Dr.ObesityLA
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Apr 19, 2025 at 4:25 PM#9

Closing the loop on my own question.

Rereading it with the dropout table open changed my view. I still think it is the most interesting molecule in the pipeline; I no longer think the 24% is the number that will end up on a label.

Last edited: Apr 19, 2025 at 5:25 PM
7 2chris_chi24, tampaLisa73, KarenAZ_mom and 4 others
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LibrarianMeg
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Apr 22, 2025 at 2:33 PM#10
Dr.NateNeph said:
The distinction that resolves most of these threads is between what is true on average and what is true for one person.

That is right, and it stops being right at the edges. The general case is well behaved; the interesting cases in this thread are all at the boundary where the general case breaks.

11 9TomFromTexas, mike.trainer_LA, sarah_nash92 and 8 others
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