🍪 CompoundTalk uses cookies to improve your experience, analyze traffic, and personalize content. By continuing to use this site, you agree to our Cookie Policy.
Evidence-based GLP-1 & peptide discussion since 2023
ForumsRetatrutide & Triple AgonistsTRIUMPH-2 obesity without diabetes — anyone have experience? Page 3

TRIUMPH-2 obesity without diabetes — anyone have experience?

Dr.ObesityLA Wed, Apr 16, 2025 at 8:08 AM 23 replies 1,941 viewsPage 3 of 5
sarah_nash92
Member
712
3,123
Jun 2024
Nashville, TN
Apr 22, 2025 at 10:20 PM#11
LindaRN_retired said:
The glucagon component looks paradoxical and is not.

Genuinely useful, thank you. I had the facts and not the framework. Adding it to my notes with a link back to this thread.

12 10NauseaFreeNow, SteveThurs, B12Beth and 9 others
Reply Quote Save Share Report
PeptideChemSF
Senior Member
1,890
9,012
Jan 2024
San Francisco, CA
Apr 23, 2025 at 6:07 AM#12

Adding the clinical framing, because it changes how the question reads. There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

Happy to go further on any of that.

13 11dave_SLC, FDA_TrackerJim, ricardo_MIA and 10 others
Reply Quote Save Share Report
JennaRN
Senior Member
1,987
8,923
Mar 2024
Colorado
Online
Apr 23, 2025 at 1:54 PM#13
Dr.NateNeph said:
The distinction that resolves most of these threads is between what is true on average and what is true for one person.

Worth saying that the confident version of this is more useful to the person writing it than to the person reading it.

14 12BiostatsBrad, PeptideSynthNJ, Dr.KarenChen and 11 others
Reply Quote Save Share Report

Janoshik Analytical — Independent Testing

Trusted third-party HPLC & mass spectrometry analysis. Verify peptide purity with the lab the community relies on. Independent. Accurate. Transparent.

Verify Your Peptides

GL Biochem (Shanghai) Ltd. — Direct Manufacturer

Est. 1998. The synthesis house behind the vials you send for testing. ISO 9001 and cGMP certified, 1,500+ staff, batch-specific COA with every order.

Browse GL Biochem
labquiet_amy
Senior Member
1,234
6,789
Mar 2024
Cambridge, MA
Apr 23, 2025 at 9:40 PM#14

One concrete data point for the thread. Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a trend.

15 13bri_stats, pete_manc_UK, anna.melb_AU and 12 others
Reply Quote Save Share Report
mike_mod
Moderator
7,234
19,823
Nov 2023
New York
Online
Apr 24, 2025 at 5:26 AM#15

Moderator note: leaving this open. It is being argued well and the disagreement is the useful part. Thread quality here is what the rules are for. Keep it up.

16 14PurityPaulOR, MaxMetOK, MounjBrad and 13 others
Reply Quote Save Share Report

Similar Threads

TRIUMPH-3 topline results — 24.2% body weight loss at 48 weeks10 replies
Retatrutide mechanism: GLP-1/GIP/glucagon triple agonism explained5 replies
Retatrutide Phase 2 dose-response analysis — optimal dose range10 replies
Glucagon receptor agonism and hepatic lipid oxidation — MASH implications13 replies
Retatrutide vs tirzepatide — dual vs triple agonist comparison22 replies
ForumsNewTrendingMembersAccount

Log In

Forgot password?
No account? Register