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Evidence-based GLP-1 & peptide discussion since 2023
ForumsLab Results & BiomarkersDo I really need bloodwork every 3 months? It is expensive — November 2025

Do I really need bloodwork every 3 months? It is expensive — November 2025

FranDenver Sat, Aug 17, 2024 at 7:44 PM 15 replies 2,046 viewsPage 1 of 3
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FranDenver
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Oct 2024
Denver, CO
Aug 17, 2024 at 7:44 PM#1

I got a full panel before starting and a repeat at three months, and the second one is more useful than the first purely because I now have something to compare against.

The narrow version of the question is how often to repeat it, because quarterly seems to be the convention and I cannot find the reasoning.

Happy to be told the question itself is wrong.

39 9Dr.RenalNash, LipidDoc_ATL, BariatricNurseD and 36 others
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Dr.AddMedPHL
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Mar 2024
Philadelphia, PA
Aug 17, 2024 at 10:11 PM#2

This one has a reasonably settled answer, so here it is. Quarterly for the first year is convention rather than evidence, and it is defensible for a simple reason: it is roughly the interval over which HbA1c becomes informative again, since it reflects about three months of glycaemia. After the first year, and once doses are stable, annual is reasonable unless something specific is being followed.

Last edited: Aug 18, 2024 at 12:11 AM
38 8sarah_nash92, FitDadDave, RunnerRach and 35 others
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claudia_zurich
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Zurich, CH
Aug 18, 2024 at 12:38 AM#3
Dr.AddMedPHL said:
Quarterly for the first year is convention rather than evidence, and it is defensible for a simple reason: it is roughly the interval over which HbA1c…

Dr.AddMedPHL has the substance of this right. The condition it depends on is worth stating. One addition: if the lab changes analytical platform between your draws, the comparison breaks and nobody tells you. It is worth asking when a value moves inexplicably.

Last edited: Aug 18, 2024 at 6:38 AM
37 7Dr.LipidDallas, alex_tucson, kevin_tulsa and 34 others
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hannah_MT
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Feb 2026
Bozeman, MT
Aug 18, 2024 at 3:05 AM#4
FranDenver said:
I got a full panel before starting and a repeat at three months, and the second one is more useful than the first purely because I now have something…

Same position here, arrived at the long way round. A defensible baseline is short: HbA1c and fasting glucose, a lipid panel with ApoB if you can get it, ALT and AST, creatinine with eGFR, TSH, ferritin and B12, and a full blood count. That set catches the things that change, the things that explain symptoms, and the things that alter the prescribing decision. Almost everything else on the long circulating lists is either invariant, uninterpretable without a specific question, or an incidental finding waiting to cause an unnecessary workup.

36 6PurityPaulOR, MaxMetOK, MounjBrad and 33 others
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chris_chi24
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Sep 2024
Chicago, IL
Aug 18, 2024 at 5:44 PM#5

Adding the clinical framing, because it changes how the question reads.

Blood work came back perfect. baseline bloodwork + this community = winning. 🏆

35 5SleepFixSam, PurityPaulOR, MaxMetOK and 32 others
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