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Evidence-based GLP-1 & peptide discussion since 2023
ForumsLab Results & BiomarkersOptimal lab testing frequency on GLP-1 — what worked for you?

Optimal lab testing frequency on GLP-1 — what worked for you?

Dr.ReproEndo Sun, Aug 4, 2024 at 10:27 PM 11 replies 1,942 viewsPage 1 of 3
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Dr.ReproEndo
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Aug 4, 2024 at 10:27 PM#1

My prescriber ordered three tests and this board recommends about twenty, and I would like to know which of those two lists is right.

The question I want answered is what actually belongs on a baseline panel, as opposed to the enormous list that gets pasted around here.

Happy to be told the question itself is wrong.

25 20mona_PHX, andrew_nyc, Dr.EndoEP and 22 others
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SarahChen_PharmD
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Aug 4, 2024 at 10:47 PM#2

This one has a reasonably settled answer, so here it is. Quarterly for the first year is convention rather than evidence, and it is defensible for a simple reason: it is roughly the interval over which HbA1c becomes informative again, since it reflects about three months of glycaemia. After the first year, and once doses are stable, annual is reasonable unless something specific is being followed.

Last edited: Aug 5, 2024 at 1:47 AM
24 19NurseKim_ATL, paul_denver, TinaHashiRN and 21 others
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lisa_labSD
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Aug 4, 2024 at 11:07 PM#3
SarahChen_PharmD said:
Quarterly for the first year is convention rather than evidence, and it is defensible for a simple reason: it is roughly the interval over which HbA1c…

That is correct as far as it goes, and here is where it stops going. One addition: if the lab changes analytical platform between your draws, the comparison breaks and nobody tells you. It is worth asking when a value moves inexplicably.

If somebody has the primary source to hand I would rather cite it than paraphrase it.

23 18Dr.PulmRoch, maya_sedona, stefan_berlin and 20 others
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wei_SG
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Aug 4, 2024 at 11:27 PM#4
Dr.ReproEndo said:
My prescriber ordered three tests and this board recommends about twenty, and I would like to know which of those two lists is right.

Same position here, arrived at the long way round. A defensible baseline is short: HbA1c and fasting glucose, a lipid panel with ApoB if you can get it, ALT and AST, creatinine with eGFR, TSH, ferritin and B12, and a full blood count. That set catches the things that change, the things that explain symptoms, and the things that alter the prescribing decision. Almost everything else on the long circulating lists is either invariant, uninterpretable without a specific question, or an incidental finding waiting to cause an unnecessary workup.

I would rather be corrected than agreed with, if it comes to it.

22 17RetaRick_CA, JenPlateau, SallyK_inj and 19 others
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Dr.ObesityMed
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Aug 5, 2024 at 1:17 AM#5

Clinical perspective, offered as context rather than as advice.

Blood work came back perfect. baseline bloodwork + this community = winning. 🏆

Last edited: Aug 5, 2024 at 7:17 AM
21 16A1cHero_PHX, Dr.RenalNash, LipidDoc_ATL and 18 others
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