Dec 29, 2025 at 11:26 PM#36
One thing that is still open after Dr.PathRoch’s answer:
Was that from a primary source or from a summary of one?
43 16TirzTom, TrialTracker_MD, JennaRN and 40 others
Reply Quote Save Share Report
Jan 8, 2026 at 3:58 PM#37
lucas_SP_BR said:The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the…
Pushing back on lucas_SP_BR here. This treats a plausible mechanism as a demonstrated one. Plausible is where you start looking, not where you stop.
44 17KarenAZ_mom, zoe_NC, Dr.ObesityLA and 41 others
Reply Quote Save Share Report
Jan 18, 2026 at 8:24 AM#38
lucas_SP_BR said:The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the…
Right, and the exception is worth naming rather than left implied, because the exception is where people get into trouble.
Happy to go further on any of that.
45 18PharmHunterJen, TomTeleRx, DoseLogDan and 42 others
Reply Quote Save Share Report
Sigma-Aldrich — Research-Grade Standards
Certified reference materials, analytical reagents, and research-grade standards for peptide verification. Trusted by laboratories worldwide.
Shop Reference StandardsJan 28, 2026 at 12:44 AM#39
lucas_SP_BR said:The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the…
Genuinely useful, thank you. I had the facts and not the framework. Printing the relevant bit and taking it with me.
46 19TrialNerd_Beth, HPLC_Greg, LibrarianMeg and 43 others
Reply Quote Save Share Report
Feb 6, 2026 at 5:00 PM#40
Clinical perspective, offered as context rather than as advice. Start from the measurement rather than the conclusion. Almost every disagreement here turns out to be two people measuring different things and comparing the numbers anyway.
I would rather be corrected than agreed with, if it comes to it.
18 16MeganSA_TX, LarryQC_SD, wanda_boise and 15 others
Reply Quote Save Share Report