Clinical perspective, offered as context rather than as advice. There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.
DanielChem_CHI said:Practical: whatever you change, write down the date and the reason.
Adding the part of the answer the thread has not reached. If two explanations both fit, the useful question is which one predicts something the other does not. That is answerable; arguing about which sounds more plausible is not.
The figures, for anyone assembling their own picture. Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a trend.
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Browse GL BiochemOne thing that is still open after DanielChem_CHI’s answer:
What did you change at the same time, and can you separate the two now?