Dr.ObesityMed said:

The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either.

Coming at Dr.ObesityMed’s question from a different direction. Worth answering the question that was asked rather than the one behind it. The narrow version usually has an answer; the broad version usually does not, and answering the broad one is how a thread stops being useful.

Adding the numbers, since they settle part of this. Keep the original post as written when you update it, and add the correction underneath. An edited-away mistake is invisible to the next person who makes it.

One thing that is still open after Dr.ObesityMed’s answer:

Did your prescriber agree with that reading, and if not what was their objection?

Dr.PulmRoch said:

Keep the original post as written when you update it, and add the correction underneath.

I read this differently. The confidence in this thread is running ahead of the evidence, and I would rather the uncertainty were stated than smoothed over because it is unsatisfying.

Dr.PulmRoch said:

Keep the original post as written when you update it, and add the correction underneath.

Agreed, with the usual condition: that holds for the average and this board is a collection of individuals. A population claim and a personal prediction are different things and get quoted interchangeably.

I would rather be corrected than agreed with, if it comes to it.