🍪 CompoundTalk uses cookies to improve your experience, analyze traffic, and personalize content. By continuing to use this site, you agree to our Cookie Policy.
Evidence-based GLP-1 & peptide discussion since 2023
ForumsSemaglutide (Ozempic / Wegovy)Novo Nordisk supply chain update — semaglutide availability Q2 2026 Page 5

Novo Nordisk supply chain update — semaglutide availability Q2 2026

Admin Mon, Feb 26, 2024 at 4:00 PM 278 replies 41,224 viewsPage 5 of 20
BethLabQueen
Senior Member
1,234
5,678
May 2024
Virginia
Online
Mar 4, 2024 at 5:04 AM#21

One concrete data point for the thread. For anyone assembling their own picture: Tmax is one to three days, terminal half-life about 165 to 170 hours, steady state at four to five weeks, and subcutaneous bioavailability near 89%. Those four numbers explain most of the questions people ask about timing.

39 12maya_sedona, stefan_berlin, Dr.EM_Chicago and 36 others
Reply Quote Save Share Report
AttorneyGrant
Member
567
2,890
Apr 2024
Washington, DC
Mar 5, 2024 at 5:37 PM#22

A narrower follow-up, since the general answer is now clear:

Whether anyone has held at a sub-maximal dose long term and kept the result, or whether the maintenance data only exists at 2.4mg?

40 13laura_annarbor, JenMemphis, pat_auckland and 37 others
Reply Quote Save Share Report
adam_van
Member
212
890
Nov 2024
Vancouver, CA
Mar 7, 2024 at 6:09 AM#23
BethLabQueen said:
For anyone assembling their own picture: Tmax is one to three days, terminal half-life about 165 to 170 hours, steady state at four to five weeks, and…

This is where I part company with the consensus forming above. Pushing back on the consensus forming here. Consistency is not the same as correctness, and a board that agrees with itself quickly is usually agreeing with the first person who sounded certain.

That is the short version; the long version is somebody else's post.

41 14LindaRN_retired, tommy_boulder, hyun_seoul and 38 others
Reply Quote Save Share Report

Janoshik Analytical — Independent Testing

Trusted third-party HPLC & mass spectrometry analysis. Verify peptide purity with the lab the community relies on. Independent. Accurate. Transparent.

Verify Your Peptides

GL Biochem (Shanghai) Ltd. — Direct Manufacturer

Est. 1998. The synthesis house behind the vials you send for testing. ISO 9001 and cGMP certified, 1,500+ staff, batch-specific COA with every order.

Browse GL Biochem
pete_nash
Member
312
1,345
Aug 2024
Nashville, TN
Mar 8, 2024 at 6:40 PM#24
BethLabQueen said:
For anyone assembling their own picture: Tmax is one to three days, terminal half-life about 165 to 170 hours, steady state at four to five weeks, and…

That is right for the common case. Whether it is right for the case being asked about depends on a detail that has not been given.

If somebody has the primary source to hand I would rather cite it than paraphrase it.

Last edited: Mar 9, 2024 at 12:40 AM
42 15SarahChen_PharmD, sarah.morrison, NeuroNate and 39 others
Reply Quote Save Share Report
alex_tucson
Member
567
2,345
May 2024
Tucson, AZ
Mar 10, 2024 at 7:10 AM#25
BethLabQueen said:
For anyone assembling their own picture: Tmax is one to three days, terminal half-life about 165 to 170 hours, steady state at four to five weeks, and…

This answered a question I did not know how to ask. Adding it to my notes with a link back to this thread.

Last edited: Mar 10, 2024 at 9:10 AM
43 16FDA_TrackerJim, ricardo_MIA, BrianDallas92 and 40 others
Reply Quote Save Share Report
13456720

Similar Threads

STEP 1-5 trials comprehensive summary — efficacy endpoints compiled12 replies
Oral semaglutide 50mg Phase 3 — OASIS program results16 replies
Semaglutide pharmacokinetics — half-life, Tmax, steady state modeling10 replies
Compounded semaglutide stability data — temperature and light sensitivity16 replies
0.25mg → 2.4mg titration: optimal schedule based on clinical data6 replies
ForumsNewTrendingMembersAccount

Log In

Forgot password?
No account? Register