MikeFit_NJ said:

Distribution matters less than total but it is not nothing.

DEXA scan update relevant to protein intake:

Scanned at months 0, 6, and 12. Here are the body comp numbers:

Lean mass preserved — actually GAINED 1-2 lbs thanks to progressive overload + 1.5g/kg protein. The protein intake discussion needs to include body comp data, not just scale weight.

One thing that is still open after PeptideChemSF’s answer:

How people are hitting a protein target on a genuinely suppressed appetite, because volume is the binding constraint rather than willingness?

PeptideSynthNJ said:

DEXA scan update relevant to protein intake: Scanned at months 0, 6, and 12.

Coming at PeptideSynthNJ’s question from a different direction. Worth answering the question that was asked rather than the one behind it. The narrow version usually has an answer; the broad version usually does not, and answering the broad one is how a thread stops being useful.

Closing the loop on my own question.

Front-loading was the answer. Same total intake, same drug, but two thirds of the protein before midday and I am hitting the target most days now.

ingrid_STO said:

Worth answering the question that was asked rather than the one behind it.

Agreed on the target, with the caveat that reference weight and current weight are different numbers. Using current weight at the start of a large loss produces a target that is both unachievable and unnecessary.