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Evidence-based GLP-1 & peptide discussion since 2023
ForumsExercise & Body CompositionBody recomposition protocol: GLP-1 + progressive overload + high protein

Body recomposition protocol: GLP-1 + progressive overload + high protein

MikeFit_NJ Sun, Jun 7, 2026 at 5:58 AM 8 replies 130 viewsPage 1 of 2
MikeFit_NJ
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Jun 7, 2026 at 5:58 AM#1

A reference post rather than a discussion. Corrections are the point; I would rather this be right than mine. It is about protein intake, and it is deliberately narrow — everything I am not confident about is marked as such.

What is actually established

Distribution matters less than total but it is not nothing. Roughly 25 to 40g per sitting with enough leucine to trigger synthesis, three or four times a day, is more effective than the same total in one enormous evening meal — and on a suppressed appetite the enormous evening meal is the one you will not finish anyway.

The condition it depends on

Anyone with reduced kidney function needs that target set by a clinician rather than a forum. High protein is safe in normal kidneys and is not automatically safe in impaired ones.

The practical version

The arithmetic that makes it tractable: reference weight in kg times 1.6 gives the target; divide by four for a per-sitting figure; then find four foods that hit that figure in a volume you can actually finish. Most people need two of the four to be liquid or semi-liquid early on.

What I am not sure about

The narrow version of the question is whether the RDA is the wrong reference entirely during rapid weight loss, and what the actual target should be. If the honest answer is that nobody knows, that is a useful answer and I would rather have it.

— MikeFit_NJ · corrections welcome and will be edited into this post with credit
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Dr.SportsMedIN
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Jun 7, 2026 at 6:30 AM#2
MikeFit_NJ said:
Distribution matters less than total but it is not nothing.

No disagreement with MikeFit_NJ. One condition attached. On a suppressed appetite the winning strategy is protein density per unit of volume, not per calorie. Isolate powders, Greek yoghurt and cottage cheese, egg whites, lean fish, and tinned tuna all deliver a lot of protein in a small physical volume. Front-load it: appetite is usually least suppressed in the first hours after waking and worst on the day or two after dosing, so get the majority in early in the day and early in the week.

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Dr.AddMedPHL
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Jun 7, 2026 at 7:02 AM#3
MikeFit_NJ said:
Distribution matters less than total but it is not nothing.

I will push back on the powder-first advice. It works and it also trains people out of eating food, and when the drug stops the habits are what remain. Getting protein from meals is slower and holds up better afterwards.

Last edited: Jun 7, 2026 at 9:02 AM
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PeptideChemSF
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Jun 7, 2026 at 7:34 AM#4

Answering the narrow version, because the broad one does not have a single answer. The RDA is the wrong reference and it is worth understanding why. 0.8 g/kg is the intake at which nitrogen balance is not negative in healthy weight-stable adults — a floor for deficiency prevention, not an optimum, and derived in a population that is not in a deficit. In a substantial energy deficit, protein requirement rises because amino acids are being oxidised for energy and because muscle protein synthesis is blunted. The literature on preserving lean mass during weight loss lands around 1.4 to 2.0 g/kg of reference body weight, which is roughly two to two and a half times the RDA.

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alex_tucson
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Jun 7, 2026 at 10:34 AM#5
Dr.SportsMedIN said:
On a suppressed appetite the winning strategy is protein density per unit of volume, not per calorie.

This is my experience too, for whatever a second data point is worth.

Last edited: Jun 7, 2026 at 12:34 PM
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