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ForumsMASH / Liver DiseaseMy liver enzyme journey — ALT from 98 to 19 on semaglutide Page 6

My liver enzyme journey — ALT from 98 to 19 on semaglutide

DerekSJ_a1c Wed, May 27, 2026 at 9:10 AM 29 replies 552 viewsPage 6 of 6
BethLabQueen
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Jun 3, 2026 at 11:28 PM#26

Adding the numbers, since they settle part of this. Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a trend.

1 24maya_sedona
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stefan_berlin
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Jun 4, 2026 at 11:34 PM#27

One thing that is still open after pat_auckland’s answer:

What did you change at the same time, and can you separate the two now?

Last edited: Jun 5, 2026 at 2:34 AM
2 0JessicaH_TX, KevinCompounds
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rachel_ABQ
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Jun 5, 2026 at 11:38 PM#28
BethLabQueen said:
Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a…

Filing a mild objection. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit. I would resist the confidence. Half of what this board was certain about two years ago has since been quietly dropped, and nobody went back to correct the threads.

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jason_paloalto
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Jun 6, 2026 at 11:43 PM#29
BethLabQueen said:
Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a…

That holds where the measurement is reliable. Where it is noisy — and a lot of what gets tracked here is noisy — the same reasoning produces confident nonsense.

4 2andrew_nyc, Dr.EndoEP, GraceAZ_72 and 1 other
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DerekSJ_a1c
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Jun 7, 2026 at 11:46 PM#30

Closing the loop on my own question.

Update since I posted: I held at 1.7mg for a further twelve weeks and lost another 4kg slowly, which settles it for me. I was escalating because the number was available, not because I had stopped responding.

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