Dr.PulmRoch said:The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the…
Agreed, with the usual condition: that holds for the average and this board is a collection of individuals. A population claim and a personal prediction are different things and get quoted interchangeably.
Dr.PulmRoch said:The boring version of this is the one that works, and the boring version is: measure a baseline, change one variable, wait, measure again under the…
This is exactly what I could not find anywhere else. I will report back once I have actually tried it.
Adding the clinical framing, because it changes how the question reads. Start from the measurement rather than the conclusion. Almost every disagreement here turns out to be two people measuring different things and comparing the numbers anyway.
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Shop Reference StandardsDr.GastroMayo said:Start from the measurement rather than the conclusion.
Coming at Dr.GastroMayo’s question from a different direction. Read four things before the headline number. The population, because trial populations are selected and supported in ways that real cohorts are not. The comparator, because "better than placebo" and "better than the current standard" are different claims and get reported identically. The primary endpoint as pre-registered, because a secondary endpoint promoted after the fact is a hypothesis rather than a finding. And the completion rate, because a large effect in the half of participants who finished is a different result from a large effect in everybody enrolled.