SarahChen_PharmD said:

Pet owner bonus of training: my dog is also losing weight because we're walking 2-3x more than before.

Exercise-induced nausea amplification with training: I learned the hard way that intense exercise within 12 hours of injection can make nausea much worse. The combination of delayed gastric emptying + exercise-induced blood flow redistribution is rough on the GI system.

My workaround: inject Friday evening, do low-intensity activity Saturday, and save my intense workouts for Tuesday-Thursday when the GI effects have subsided. Timing your training around your injection schedule is a real optimization strategy.

Adding the numbers, since they settle part of this. Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a trend.

NeuroNate said:

Exercise-induced nausea amplification with training: I learned the hard way that intense exercise within 12 hours of injection can make nausea much…

Adding the part of the answer the thread has not reached. The distinction that resolves most of these threads is between what is true on average and what is true for one person. Both are real; they answer different questions and get quoted as if they were the same one.

One thing that is still open after tommy_boulder’s answer:

How would you tell the difference between that and the alternative explanation?

OP back with an update, since a thread like this is useless without one.

For the archive: it took about six weeks rather than the two I expected, and the difference between those two numbers was the whole of my problem.