One thing that is still open after Dr.EM_Chicago’s answer:
How would you tell the difference between that and the alternative explanation?
anders_CPH said:Practical: whatever you change, write down the date and the reason.
I do not accept the framing. The question has been narrowed to the version that has a tidy answer, and the part that was dropped is the part the OP actually asked about.
anders_CPH said:Practical: whatever you change, write down the date and the reason.
Correct, and worth adding that it is reversible. Nothing being described here is a one-way door, which changes how cautious it is reasonable to be.
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Browse GL Biochemanders_CPH said:Practical: whatever you change, write down the date and the reason.
That reframing is the part I needed.
Adding the clinical framing, because it changes how the question reads. The distinction that resolves most of these threads is between what is true on average and what is true for one person. Both are real; they answer different questions and get quoted as if they were the same one.