One thing that is still open after andrew_nyc’s answer:
How would you tell the difference between that and the alternative explanation?
KevinCompounds said:Muscle fiber type changes during GLP-1-mediated weight loss, relevant to lean mass: preliminary biopsy data suggests that weight loss shifts the…
Sharing my comprehensive lab data relevant to lean mass:
| Biomarker | Baseline | Month 3 | Month 6 | Month 9 |
|---|---|---|---|---|
| Weight (lbs) | 267 | 232 | 217 | 217 |
| A1C (%) | 7.2 | 6.7 | 5.6 | 5.4 |
| hsCRP (mg/L) | 7.0 | 4.0 | 2.5 | 1.3 |
| Triglycerides | 217 | 187 | 127 | 97 |
Protocol: Tirzepatide 15mg/wk, resistance training 4x/week, protein 1.6g/kg/day.
The improvements in lean mass are clearly reflected in these numbers. The inflammatory marker reduction (hsCRP) is particularly striking.
KevinCompounds said:Muscle fiber type changes during GLP-1-mediated weight loss, relevant to lean mass: preliminary biopsy data suggests that weight loss shifts the…
Back pain as a lean mass side effect: not from the medication itself, but from rapid body composition changes. Losing 63 lbs shifts your center of gravity and your core muscles need time to adjust.
Physical therapy has been essential. Core strengthening exercises (planks, dead bugs, bird dogs) daily for 10 minutes have eliminated my lower back pain. Your body is literally relearning how to carry itself.
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Browse GL BiochemKevinCompounds said:Muscle fiber type changes during GLP-1-mediated weight loss, relevant to lean mass: preliminary biopsy data suggests that weight loss shifts the…
This is exactly what I could not find anywhere else.
From the other side of the consultation, briefly. It helps to ask what evidence would change your mind before you look at any. If nothing would, the discussion is not about evidence, and it is better to say so early than to spend nine posts discovering it.