PeptideChemSF said:

Bone density monitoring on lean mass: DEXA bone density at baseline and month 12.

Same experience, arrived at from the opposite direction. Posting only so the count is not one.

Adding the clinical framing, because it changes how the question reads.

My endo's protocol for lean mass plateau: if weight loss stalls for 6+ weeks at current dose, we go through this checklist before titrating up:

1. Food diary review — is intake creeping up?
2. Protein check — minimum 100g/day
3. Activity audit — steps + resistance training
4. Sleep quality — poor sleep kills GLP-1 efficacy
5. Stress/cortisol management

Only after addressing all of these do we increase the dose. Often fixing one lifestyle factor restarts progress without needing more medication.

roxy_nash said:

My endo's protocol for lean mass plateau: if weight loss stalls for 6+ weeks at current dose, we go through this checklist before titrating up: Food…

This is my experience too, for whatever a second data point is worth. Nothing to add that would improve it.

roxy_nash said:

My endo's protocol for lean mass plateau: if weight loss stalls for 6+ weeks at current dose, we go through this checklist before titrating up: Food…

OMG yes. lean mass + resistance training is the combo. Can confirm.

Moderator note: the sourcing question belongs in the vendor section and has been split out. Tagging this one for the weekly digest.