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ForumsSemaglutide (Ozempic / Wegovy)Semaglutide and exercise performance — what worked for you? Page 7

Semaglutide and exercise performance — what worked for you?

Dr.PainCLE Sat, Jul 12, 2025 at 7:21 AM 54 replies 2,566 viewsPage 7 of 11
anders_CPH
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Feb 2024
Copenhagen, DK
Jul 26, 2025 at 8:06 AM#31

A narrower follow-up, since the general answer is now clear:

How much of the between-person variation is pharmacokinetic and how much is just adherence measured badly?

Last edited: Jul 26, 2025 at 12:06 PM
17 15CryptoCarl, MariaRD, AussieAnna and 14 others
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SallyK_inj
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Jul 2024
Iowa
Jul 27, 2025 at 8:44 AM#32
Dr.PainCLE said:
Following this thread I went back and re-read the extension data properly.

Worth saying that the confident version of this is more useful to the person writing it than to the person reading it.

18 16bbq_ray_KC, oliver_london, tane_welly and 15 others
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tom_AK
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Jan 2026
Anchorage, AK
Jul 28, 2025 at 9:22 AM#33
Dr.PainCLE said:
Following this thread I went back and re-read the extension data properly.

Agreed, and the size of the effect matters as much as its existence. Something real and small gets treated here as though it were real and decisive.

Correct me if the detail matters more than I have assumed.

Last edited: Jul 28, 2025 at 1:22 PM
19 17tyler_CSCS, VanRx_Mike, steve_okc and 16 others
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pete_nash
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Aug 2024
Nashville, TN
Jul 29, 2025 at 9:59 AM#34
Dr.PainCLE said:
Following this thread I went back and re-read the extension data properly.

This answered a question I did not know how to ask.

Last edited: Jul 29, 2025 at 3:59 PM
20 18SarahChen_PharmD, sarah.morrison, NeuroNate and 17 others
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Dr.EndoIndy
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Oct 2024
Indianapolis, IN
Jul 30, 2025 at 10:35 AM#35

Adding the clinical framing, because it changes how the question reads. The mechanism and the magnitude are separate questions. Agreeing that something happens says nothing about whether it happens enough to act on.

21 19SandraNC_45, Dr.EndoIndy, tom_AK and 18 others
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