A narrower follow-up, since the general answer is now clear:
How much of the between-person variation is pharmacokinetic and how much is just adherence measured badly?
A narrower follow-up, since the general answer is now clear:
How much of the between-person variation is pharmacokinetic and how much is just adherence measured badly?
Dr.PainCLE said:Following this thread I went back and re-read the extension data properly.
Worth saying that the confident version of this is more useful to the person writing it than to the person reading it.
Dr.PainCLE said:Following this thread I went back and re-read the extension data properly.
Agreed, and the size of the effect matters as much as its existence. Something real and small gets treated here as though it were real and decisive.
Correct me if the detail matters more than I have assumed.
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Browse GL BiochemDr.PainCLE said:Following this thread I went back and re-read the extension data properly.
This answered a question I did not know how to ask.
Adding the clinical framing, because it changes how the question reads. The mechanism and the magnitude are separate questions. Agreeing that something happens says nothing about whether it happens enough to act on.