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ForumsProgress & Lab ResultsCRP from 12.4 to 0.8 — inflammation before and after GLP-1

CRP from 12.4 to 0.8 — inflammation before and after GLP-1

DataDave Sat, May 23, 2026 at 4:32 PM 32 replies 970 viewsPage 1 of 7
DataDave
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May 23, 2026 at 4:32 PM#1

Thirteen weeks at the same dose with no change on the scale, and I have gone from assuming it was the drug to assuming it was me and back several times.

What would genuinely help is knowing how to distinguish a genuine plateau from measurement noise and creeping intake, before changing anything.

I would rather have one careful answer than five confident ones.

9 4VendorMark, COA_Karl, MikeFit_NJ and 6 others
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COA_Karl
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May 23, 2026 at 4:37 PM#2
DataDave said:
Thirteen weeks at the same dose with no change on the scale, and I have gone from assuming it was the drug to assuming it was me and back several…

Plateau breaking story with a stall: I stalled at 219 lbs for 6 weeks. Tried everything — calorie cycling, increased exercise, more water. Nothing worked.

What finally broke the plateau: increasing protein to 150g/day. Lost 5 lbs in the next 2 weeks. Plateaus are temporary — they always break if you stay consistent.

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PeptideChemSF
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May 23, 2026 at 4:42 PM#3
COA_Karl said:
Plateau breaking story with a stall: I stalled at 219 lbs for 6 weeks.

COA_Karl has the substance of this right. The condition it depends on is worth stating. Genuine plateaus happen too, and the mechanism is metabolic adaptation plus a smaller body. A body 20kg lighter needs meaningfully fewer calories at rest and less to move, so the deficit that produced the first phase is arithmetically smaller now. The options are the honest ones — increase the deficit slightly, increase activity, or accept the new plateau — and escalating the dose is only one of them.

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TinaHashiRN
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May 23, 2026 at 4:46 PM#4
DataDave said:
Thirteen weeks at the same dose with no change on the scale, and I have gone from assuming it was the drug to assuming it was me and back several…

Same pattern here, and in the same order. Nothing to add that would improve it.

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anna.melb_AU
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May 23, 2026 at 5:12 PM#5

Adding the clinical framing, because it changes how the question reads. It helps to say which part of this you are uncertain about. A precise question gets a precise answer; a general one gets everybody’s favourite anecdote.

Last edited: May 23, 2026 at 9:12 PM
5 0Dr.LipidDallas, alex_tucson, kevin_tulsa and 2 others
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