LondonLisa said:

Training does two things here and only one of them is on the scale.

Exercise-induced nausea amplification with training: I learned the hard way that intense exercise within 12 hours of injection can make nausea much worse. The combination of delayed gastric emptying + exercise-induced blood flow redistribution is rough on the GI system.

My workaround: inject Friday evening, do low-intensity activity Saturday, and save my intense workouts for Tuesday-Thursday when the GI effects have subsided. Timing your training around your injection schedule is a real optimization strategy.

One thing that is still open after anna.melb_AU’s answer:

Did your prescriber agree with that reading, and if not what was their objection?

TirzTom said:

Exercise-induced nausea amplification with training: I learned the hard way that intense exercise within 12 hours of injection can make nausea much…

There is a second half to this that has not been said yet. The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either. Those three things can all be true at once, and most arguments here are two people holding different parts of that.

Closing the loop on my own question.

For the archive: it took about six weeks rather than the two I expected, and the difference between those two numbers was the whole of my problem.

roxy_nash said:

The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either.

No disagreement, though it depends on where somebody is starting from, and this thread has been assuming a starting point nobody stated.