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ForumsSemaglutide (Ozempic / Wegovy)STEP 1-5 trials comprehensive summary — my results so far Page 4

STEP 1-5 trials comprehensive summary — my results so far

ben_calgary Wed, Apr 16, 2025 at 10:35 AM 40 replies 2,086 viewsPage 4 of 8
NurseKim_ATL
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Apr 25, 2025 at 4:57 PM#16
LipidDoc_ATL said:
ben_calgary said: ...but the FDA says semaglutide...

Agreed, and subgroup analyses deserve particular suspicion. With enough subgroups something is significant by chance, and pre-registered subgroups are a different animal from ones found afterwards.

19 17denise_HTX, raj_cambridge, ingrid_STO and 16 others
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VendorMark
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Apr 26, 2025 at 7:47 AM#17
lisa_labSD said:
A quick sanity check on any figure quoted here: is it mean or median, is it intention-to-treat or completers, and what was the comparator.

This answered a question I did not know how to ask. Printing the relevant bit and taking it with me.

20 18KristenIndy, MarkLI_maint, Dr.PeteFamMed and 17 others
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Dr.PeteFamMed
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Apr 26, 2025 at 10:37 PM#18

Clinical perspective, offered as context rather than as advice. Start from the measurement rather than the conclusion. Almost every disagreement here turns out to be two people measuring different things and comparing the numbers anyway.

Last edited: Apr 26, 2025 at 11:37 PM
21 19LindaRN_retired, tommy_boulder, hyun_seoul and 18 others
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quinn_sf
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Apr 27, 2025 at 1:26 PM#19
Dr.PeteFamMed said:
Start from the measurement rather than the conclusion.

Second this.

Last edited: Apr 27, 2025 at 7:26 PM
22 20andrew_nyc, Dr.EndoEP, GraceAZ_72 and 19 others
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Admin
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Apr 28, 2025 at 4:15 AM#20

Moderator note: a post naming a supplier has been edited. Discuss suppliers in the review sections, not here. No action needed from anybody.

44 17PeptideSynthNJ, Dr.KarenChen, Dr.NateNeph and 41 others
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