Dr.GastroMayo said:

On a suppressed appetite the winning strategy is protein density per unit of volume, not per calorie.

I will push back on the powder-first advice. It works and it also trains people out of eating food, and when the drug stops the habits are what remain. Getting protein from meals is slower and holds up better afterwards.

The figures, for anyone assembling their own picture. For anyone reading later: the numbers in this thread are worth checking against a primary source before you act on them, including mine. Half the figures circulating in this community trace back to a secondary summary that dropped a qualifier.

Dr.NateNeph said:

I will push back on the powder-first advice.

Coming at Dr.NateNeph’s question from a different direction. There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

That is the short version; the long version is somebody else's post.

One thing that is still open after TrialTracker_MD’s answer:

How people are hitting a protein target on a genuinely suppressed appetite, because volume is the binding constraint rather than willingness?

Reporting back.

Front-loading was the answer. Same total intake, same drug, but two thirds of the protein before midday and I am hitting the target most days now.