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ForumsSemaglutide (Ozempic / Wegovy)Semaglutide mechanism of action: hypothalamic GLP-1R binding and satiety — what worked for you? Page 8

Semaglutide mechanism of action: hypothalamic GLP-1R binding and satiety — what worked for you?

VendorMark Fri, Jan 31, 2025 at 9:53 PM 54 replies 2,401 viewsPage 8 of 11
newstart_MO
New Member
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Feb 2026
Springfield, MO
May 1, 2025 at 10:41 PM#36
Dr.PathRoch said:
If you are comparing against somebody else’s result, check that you are comparing the same measurement taken the same way.

Worth saying that the confident version of this is more useful to the person writing it than to the person reading it.

10 8bri_stats, pete_manc_UK, anna.melb_AU and 7 others
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RunnerRach
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Aug 2024
Boston, MA
May 6, 2025 at 8:40 PM#37
Dr.PathRoch said:
If you are comparing against somebody else’s result, check that you are comparing the same measurement taken the same way.

Right, and the exception is worth naming rather than left implied, because the exception is where people get into trouble.

11 9MikeKY_noInsulin, Dr.RaviCardio, jennifer_SEA and 8 others
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KarenAZ_mom
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2,567
Aug 2024
Scottsdale, AZ
May 11, 2025 at 6:36 PM#38
Dr.PathRoch said:
If you are comparing against somebody else’s result, check that you are comparing the same measurement taken the same way.

Genuinely useful, thank you. I had the facts and not the framework. I will report back once I have actually tried it.

Last edited: May 11, 2025 at 11:36 PM
12 10bri_stats, pete_manc_UK, anna.melb_AU and 9 others
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carl_compliance
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Nov 2024
Raleigh, NC
May 16, 2025 at 4:29 PM#39

Clinical perspective, offered as context rather than as advice. The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either. Those three things can all be true at once, and most arguments here are two people holding different parts of that.

Ask again with the specifics and you will get a better answer than this one.

Last edited: May 16, 2025 at 7:29 PM
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DoseLogDan
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567
Feb 2025
Montana
May 21, 2025 at 2:19 PM#40
carl_compliance said:
The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either.

Same experience, arrived at from the opposite direction. Posting only so the count is not one.

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