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ForumsSemaglutide (Ozempic / Wegovy)Sema fatigue at month 6 — what worked for you?

Sema fatigue at month 6 — what worked for you?

mike_mealprep Mon, Jul 22, 2024 at 3:58 PM 52 replies 2,218 viewsPage 1 of 11
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mike_mealprep
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Jul 22, 2024 at 3:58 PM#1

I am tired in a way that does not respond to sleep, which is different from the tiredness I had before any of this started.

Worth checking before concluding it is the drug: ferritin, B12, TSH, and total intake for three honest days. Two of those four explain most cases.

The bit I cannot resolve on my own is whether the fatigue is a direct drug effect or simply the caloric deficit, because the answer changes what you do about it.

Tell me what I have not thought of.

31 1mia_MS2, LeilaHI, marcus_mpls and 28 others
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KevinCompounds
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Jul 22, 2024 at 4:44 PM#2

Taking the question as asked, rather than the general version of it. Take it one variable at a time. Almost every unanswerable question in these threads is unanswerable because three things changed in the same fortnight, and no amount of subsequent argument can untangle them after the fact.

Happy to go further on any of that.

30 0Dr.RaviCardio, jennifer_SEA, tyler_CSCS and 27 others
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kate.chem
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Jul 22, 2024 at 5:30 PM#3
KevinCompounds said:
Almost every unanswerable question in these threads is unanswerable because three things changed in the same fortnight, and no amount of subsequent…

Agreed on the substance. I would put less weight on the timescale, because two months of anything is not enough to distinguish a trend from a wobble.

Last edited: Jul 22, 2024 at 8:30 PM
29 24tyler_CSCS, VanRx_Mike, steve_okc and 26 others
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PedsEndoPhilly
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Jul 22, 2024 at 6:16 PM#4
mike_mealprep said:
I am tired in a way that does not respond to sleep, which is different from the tiredness I had before any of this started.

This is my experience too, for whatever a second data point is worth. I had assumed I was the exception until I read this.

Last edited: Jul 22, 2024 at 11:16 PM
28 23Dr.LeslieOBGYN, MikeNYC_runner and 25 others
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Dr.PeteFamMed
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Jul 22, 2024 at 10:38 PM#5

Clinical perspective, offered as context rather than as advice. The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either. Those three things can all be true at once, and most arguments here are two people holding different parts of that.

Last edited: Jul 22, 2024 at 11:38 PM
27 22FranDenver, Dr.BariatricHTX, LindaRN_retired and 24 others
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