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ForumsSide Effects & ManagementKidney stone risk on GLP-1 — 6 month update Page 3

Kidney stone risk on GLP-1 — 6 month update

steve_okc Tue, Dec 9, 2025 at 5:29 AM 12 replies 1,200 viewsPage 3 of 3
BethLabQueen
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Dec 11, 2025 at 1:44 AM#11
NurseAsh_DET said:
Electrolyte monitoring on hydration — especially important during early titration when GI effects are most pronounced: Sodium: 138 mEq/L (normal, but…

Correct, and worth adding that it is reversible. Nothing being described here is a one-way door, which changes how cautious it is reasonable to be.

26 24maya_sedona, stefan_berlin, Dr.EM_Chicago and 23 others
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DadBodDave
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Dec 11, 2025 at 11:46 AM#12
pam_stl said:
Agreed, and the practical implication is not to over-read a single eGFR during a period of rapid loss and altered hydration.

Bookmarking. The distinction being drawn above is the one nobody else makes. Adding it to my notes with a link back to this thread.

Last edited: Dec 11, 2025 at 2:46 PM
27 0JenMemphis, pat_auckland, Dr.GastroMayo and 24 others
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emily_PDX
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Dec 11, 2025 at 9:48 PM#13
NurseAsh_DET said:
Electrolyte monitoring on hydration — especially important during early titration when GI effects are most pronounced: Sodium: 138 mEq/L (normal, but…

I am going to disagree with the direction of travel here. The thread has converged on the tidiest answer rather than the best-supported one, and those are not the same thing.

28 1Dr.NateNeph, PharmD_Rodriguez, julia.endo and 25 others
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DanielChem_CHI
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Dec 12, 2025 at 7:49 AM#14

The figures, for anyone assembling their own picture. For anyone reading later: the numbers in this thread are worth checking against a primary source before you act on them, including mine. Half the figures circulating in this community trace back to a secondary summary that dropped a qualifier.

29 2ben_calgary, patPC_UT, Dr.DermMIA and 26 others
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mike_mod
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Dec 12, 2025 at 5:50 PM#15

Moderator note: the sourcing question belongs in the vendor section and has been split out.

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