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ForumsMASH / Liver DiseaseMASH biomarker panel — looking for input Page 7

MASH biomarker panel — looking for input

tammy_FL Wed, Apr 16, 2025 at 3:46 PM 31 replies 2,203 viewsPage 7 of 7
LabKate
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Jun 23, 2025 at 10:19 PM#31
Dr.PathRoch said:
If you are going to change something, change one thing and give it long enough to express itself.

That is right, and it stops being right at the edges. The general case is well behaved; the interesting cases in this thread are all at the boundary where the general case breaks.

15 13JenMemphis, pat_auckland, Dr.GastroMayo and 12 others
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mike_nyc
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Jun 29, 2025 at 9:16 AM#32
Dr.PathRoch said:
If you are going to change something, change one thing and give it long enough to express itself.

Genuinely useful, thank you. I had the facts and not the framework. Adding it to my notes with a link back to this thread.

Last edited: Jun 29, 2025 at 1:16 PM
16 14stefan_berlin, Dr.EM_Chicago, pete_RVA and 13 others
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lisa_labSD
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Jul 4, 2025 at 8:16 PM#33

Adding the clinical framing, because it changes how the question reads. It is worth asking what the claim would look like if it were false. If nothing would look different, it is not a claim about the world and no amount of discussion will settle it.

17 15Dr.PulmRoch, maya_sedona, stefan_berlin and 14 others
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kate.chem
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Jul 10, 2025 at 7:19 AM#34
lisa_labSD said:
It is worth asking what the claim would look like if it were false.

Can confirm. Same sequence, different timescale. I had assumed I was the exception until I read this.

Last edited: Jul 10, 2025 at 10:19 AM
18 16jennifer_SEA, tyler_CSCS, VanRx_Mike and 15 others
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MikeNYC_runner
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Jul 15, 2025 at 6:25 PM#35
lisa_labSD said:
It is worth asking what the claim would look like if it were false.

Adding the part of the answer the thread has not reached. Worth answering the question that was asked rather than the one behind it. The narrow version usually has an answer; the broad version usually does not, and answering the broad one is how a thread stops being useful.

Correct me if the detail matters more than I have assumed.

19 17MASHdoc_SA, GenomicsKate, Dr.ObesityMed and 16 others
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