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Evidence-based GLP-1 & peptide discussion since 2023
ForumsSide Effects & ManagementWhen to stop GLP-1 — need advice Page 5

When to stop GLP-1 — need advice

pam_stl Mon, Oct 20, 2025 at 2:04 AM 39 replies 1,952 viewsPage 5 of 8
PharmacoVig_BOS
Senior Member
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Feb 2024
Boston, MA
Oct 28, 2025 at 9:42 PM#21

Adding the numbers, since they settle part of this. Practical: whatever you change, write down the date and the reason. In three months the reason is what you will have forgotten, and the reason is what makes the record worth having.

Last edited: Oct 29, 2025 at 12:42 AM
25 23amsterdam_pete, LondonLisa, mike_nyc and 22 others
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Dr.EndoEP
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Oct 2024
El Paso, TX
Oct 31, 2025 at 5:34 AM#22

A narrower follow-up, since the general answer is now clear:

What would you measure differently if you were starting again?

26 24james_edin, FranDenver, Dr.BariatricHTX and 23 others
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JessicaM_2024
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Mar 2024
Portland, OR
Nov 2, 2025 at 1:27 PM#23
PharmacoVig_BOS said:
Practical: whatever you change, write down the date and the reason.

This is where I part company with the consensus forming above. Filing an objection on the n=1 problem. Personal experience is genuine evidence about one person and very weak evidence about anybody else, and this thread keeps promoting the first into the second.

27 0mike_mealprep, NicoleRaleigh, james_edin and 24 others
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wendy_avl
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Oct 2024
Asheville, NC
Nov 4, 2025 at 9:22 PM#24
PharmacoVig_BOS said:
Practical: whatever you change, write down the date and the reason.

No disagreement, though the timescale matters more than the mechanism here. Most of what looks like a difference in kind turns out to be a difference in how long somebody waited.

28 1PharmHunterJen, TomTeleRx, DoseLogDan and 25 others
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Dr.NephBHM_UK
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Jun 2024
Birmingham, UK
Nov 7, 2025 at 5:18 AM#25
PharmacoVig_BOS said:
Practical: whatever you change, write down the date and the reason.

Bookmarking. The distinction being drawn above is the one nobody else makes.

29 2PeptideChemSF, A1cHero_PHX, Dr.RenalNash and 26 others
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