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ForumsSemaglutide (Ozempic / Wegovy)Heart rate increase on sema — what worked for you? Page 4

Heart rate increase on sema — what worked for you?

GraceAZ_72 Fri, Apr 5, 2024 at 2:21 AM 66 replies 3,533 viewsPage 4 of 14
Dr.RheumBOS
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Apr 6, 2024 at 4:49 PM#16

Adding the clinical framing, because it changes how the question reads. Take it one variable at a time. Almost every unanswerable question in these threads is unanswerable because three things changed in the same fortnight, and no amount of subsequent argument can untangle them after the fact.

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stefan_berlin
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Apr 6, 2024 at 10:29 PM#17

Adding the numbers, since they settle part of this. If you are going to change something, change one thing and give it long enough to express itself. Four weeks is the usual minimum for anything pharmacological on this board, and two weeks of data has told you almost nothing.

Last edited: Apr 7, 2024 at 1:29 AM
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NauseaFreeNow
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Apr 7, 2024 at 4:09 AM#18

Following on from josh_phd_bmore — and this may be the naive question:

Did your prescriber agree with that reading, and if not what was their objection?

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tony_orlando
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Apr 7, 2024 at 9:49 AM#19
stefan_berlin said:
If you are going to change something, change one thing and give it long enough to express itself.

Filing a mild objection. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit. Albumin binding above 99% is the whole reason weekly dosing works, and it is also why the trough matters more than the peak. People who dose late are not losing a peak, they are letting the trough fall, and the appetite effect tracks the trough.

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mike_mod
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Apr 7, 2024 at 3:29 PM#20

Moderator note: good thread. Keeping it here rather than moving it, because the question is general enough to be useful. Report rather than reply if it drifts again.

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