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ForumsMASH / Liver DiseaseALT normalization rates on GLP-1 — my results so far Page 3

ALT normalization rates on GLP-1 — my results so far

Dr.NephBHM_UK Sun, Nov 24, 2024 at 9:26 AM 11 replies 1,671 viewsPage 3 of 3
Dr.RenalNash
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Nov 27, 2024 at 5:13 AM#11
EndoResFellow said:
Worth answering the question that was asked rather than the one behind it.

Agreed, and one caution: a single measurement is not a measurement. Anything that moves day to day needs a trend before it means anything at all.

8 6wei_SG, cory_ATX, lori_vegas and 5 others
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tyler_CSCS
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Phoenix, AZ
Nov 28, 2024 at 8:32 PM#12
HealthEcon_DC said:
NASH/MAFLD therapeutic landscape and liver and MASH: GLP-1 agonists are emerging as potential first-line NASH therapy.

This answered a question I did not know how to ask. Printing the relevant bit and taking it with me.

9 7hannah_MT, Dr.SportsMedIN, amy_econ_NJ and 6 others
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PharmacoVig_BOS
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Boston, MA
Nov 30, 2024 at 11:50 AM#13
EndoResFellow said:
Worth answering the question that was asked rather than the one behind it.

Filing a mild objection. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit. This treats a plausible mechanism as a demonstrated one. Plausible is where you start looking, not where you stop.

10 8DataDave, Dr.GutHealth, amsterdam_pete and 7 others
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lisa_labSD
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Oct 2024
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Dec 2, 2024 at 3:08 AM#14

One concrete data point for the thread. Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a trend.

11 9lori_vegas, Dr.PulmRoch, maya_sedona and 8 others
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mike_mod
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Dec 3, 2024 at 6:25 PM#15

Moderator note: a post naming a supplier has been edited. Discuss suppliers in the review sections, not here. Tagging this one for the weekly digest.

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