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Evidence-based GLP-1 & peptide discussion since 2023
ForumsMASH / Liver DiseaseMy liver enzyme journey — looking for input Page 3

My liver enzyme journey — looking for input

Dr.KarenChen Tue, Jul 9, 2024 at 5:54 PM 39 replies 2,351 viewsPage 3 of 8
NurseAsh_DET
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Jul 10, 2024 at 5:32 AM#11
carl_compliance said:
Liver ultrasound comparison for liver and MASH: my hepatologist ordered serial ultrasounds to track NAFLD regression.

Thank you for spelling out the reasoning rather than just the conclusion. Sending this to two other people who asked me the same thing last week.

25 23FDA_TrackerJim, ricardo_MIA, BrianDallas92 and 22 others
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NurseKim_ATL
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Jul 10, 2024 at 8:19 AM#12

From the other side of the consultation, briefly. Whatever the answer turns out to be, the method for getting there is the same: state the assumption, do the arithmetic in public, and invite the correction. That is slower than asserting, and it is the only version that survives being wrong.

Last edited: Jul 10, 2024 at 1:19 PM
26 24raj_cambridge, ingrid_STO, pete_nash and 23 others
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mike_nyc
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Jul 10, 2024 at 11:06 AM#13
Dr.EndoIndy said:
NASH/MAFLD therapeutic landscape and liver and MASH: GLP-1 agonists are emerging as potential first-line NASH therapy.

Careful with the causal language. Two things moving together in a period when five things changed is not a mechanism, and stating it as one makes the thread less useful to somebody reading it later.

If somebody has the primary source to hand I would rather cite it than paraphrase it.

27 0Dr.EM_Chicago, pete_RVA, CarlaRPh_TPA and 24 others
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hank_denver
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Jul 10, 2024 at 1:53 PM#14

One concrete data point for the thread. If you are comparing against somebody else’s result, check that you are comparing the same measurement taken the same way. Most of the apparent contradictions in these threads dissolve at that step.

28 1fiona_VT, denise_HTX, raj_cambridge and 25 others
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mike_mod
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Jul 10, 2024 at 4:40 PM#15

Moderator note: the sourcing question belongs in the vendor section and has been split out. Report rather than reply if it drifts again.

Last edited: Jul 10, 2024 at 6:40 PM
29 2PurityPaulOR, MaxMetOK, MounjBrad and 26 others
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