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ForumsMASH / Liver DiseaseMy liver enzyme journey — looking for input Page 5

My liver enzyme journey — looking for input

Dr.KarenChen Tue, Jul 9, 2024 at 5:54 PM 39 replies 2,351 viewsPage 5 of 8
fiona_VT
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Jul 11, 2024 at 9:20 AM#21

One thing that is still open after Dr.GastroMayo’s answer:

Did your prescriber agree with that reading, and if not what was their objection?

6 4mark_tokyo, hans_munich, jason_sac26 and 3 others
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AussieAnna
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Jul 11, 2024 at 5:56 PM#22
sophie_paris said:
The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either.

I read this differently from sophie_paris, on substance rather than tone. The counter-case has not been addressed. Somebody upthread described the situation that does not fit, and the thread moved on rather than engaging with it, which is the failure mode this board is supposed to avoid.

Correct me if the detail matters more than I have assumed.

7 5HPLC_Greg, LibrarianMeg, bri_stats and 4 others
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Dr.NephBHM_UK
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Jul 12, 2024 at 2:32 AM#23
sophie_paris said:
The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either.

That is right for the common case. Whether it is right for the case being asked about depends on a detail that has not been given.

8 6PharmacoVig_BOS, SurmountFan_IN, PeptideChemSF and 5 others
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anna.melb_AU
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Jul 12, 2024 at 11:08 AM#24
sophie_paris said:
The honest answer is that the effect is real, the magnitude is contested, and the individual variation is larger than either.

Bookmarking. The distinction being drawn above is the one nobody else makes. Adding it to my notes with a link back to this thread.

9 7tammy_FL, Dr.LipidDallas, alex_tucson and 6 others
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Dr.NateNeph
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Jul 12, 2024 at 7:43 PM#25

Adding the clinical framing, because it changes how the question reads. It helps to ask what evidence would change your mind before you look at any. If nothing would, the discussion is not about evidence, and it is better to say so early than to spend nine posts discovering it.

10 8RickReta_CO, PharmHunterJen, TomTeleRx and 7 others
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