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Evidence-based GLP-1 & peptide discussion since 2023
ForumsProgress & Lab ResultsHas anyone dealt with one hundred pounds down lets gooo? Page 3

Has anyone dealt with one hundred pounds down lets gooo?

DanielChem_CHI Tue, Apr 15, 2025 at 5:09 PM 25 replies 1,966 viewsPage 3 of 5
ZaraB_AL
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Apr 17, 2025 at 4:12 AM#11
pete_nash said:
Genuine plateaus happen too, and the mechanism is metabolic adaptation plus a smaller body.

This answered a question I did not know how to ask.

10 8JessicaH_TX, KevinCompounds, TirzTom and 7 others
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PharmHunterJen
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Apr 17, 2025 at 11:51 AM#12

Clinical perspective, offered as context rather than as advice. The distinction that resolves most of these threads is between what is true on average and what is true for one person. Both are real; they answer different questions and get quoted as if they were the same one.

11 9alex_tucson, kevin_tulsa, Dr.PainCLE and 8 others
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LabKate
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Apr 17, 2025 at 7:30 PM#13
EndoResFellow said:
Worth answering the question that was asked rather than the one behind it.

This is where I part company with the consensus forming above. Filing an objection on the n=1 problem. Personal experience is genuine evidence about one person and very weak evidence about anybody else, and this thread keeps promoting the first into the second.

12 10Dr.SleepRoch, laura_annarbor, JenMemphis and 9 others
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quinn_sf
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Apr 18, 2025 at 3:08 AM#14

One concrete data point for the thread. Say what you would expect to see if you were wrong, before you look. It is a small discipline and it changes what you notice.

13 11andrew_nyc, Dr.EndoEP, GraceAZ_72 and 10 others
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mike_mod
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Apr 18, 2025 at 10:46 AM#15

Moderator note: good thread. Keeping it here rather than moving it, because the question is general enough to be useful. No action needed from anybody.

14 12PurityPaulOR, MaxMetOK, MounjBrad and 11 others
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