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Evidence-based GLP-1 & peptide discussion since 2023
ForumsSide Effects & ManagementInsomnia on semaglutide — need advice Page 6

Insomnia on semaglutide — need advice

wei_SG Tue, Dec 17, 2024 at 5:21 AM 34 replies 1,822 viewsPage 6 of 7
EndoResFellow
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Baltimore, MD
Dec 23, 2024 at 3:31 PM#26
anna.melb_AU said:
It helps to ask what evidence would change your mind before you look at any.

Mine went the same way, slower.

47 20robert_kc, dan_philly, MeganSA_TX and 44 others
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TinaHashiRN
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Sep 2024
Raleigh, NC
Dec 24, 2024 at 12:03 AM#27
anna.melb_AU said:
It helps to ask what evidence would change your mind before you look at any.

There is a second half to this that has not been said yet. The distinction that resolves most of these threads is between what is true on average and what is true for one person. Both are real; they answer different questions and get quoted as if they were the same one.

48 21mike_mod, SarahChen_PharmD, sarah.morrison and 45 others
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DoseLogDan
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Feb 2025
Montana
Dec 24, 2024 at 8:34 AM#28

Adding the numbers, since they settle part of this. If you are going to change something, change one thing and give it long enough to express itself. Four weeks is the usual minimum for anything pharmacological on this board, and two weeks of data has told you almost nothing.

49 22mel_PDX, Dr.AddMedPHL, newstart_MO and 46 others
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A1cHero_PHX
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Phoenix, AZ
Dec 24, 2024 at 5:05 PM#29

A narrower follow-up, since the general answer is now clear:

What the dose-response curve actually looks like above 1.7mg, because the trial means hide how few people account for the extra loss?

50 23chris_chi24, tampaLisa73, KarenAZ_mom and 47 others
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wei_SG
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Nov 2024
Singapore, SG
Dec 25, 2024 at 1:36 AM#30

OP back with an update, since a thread like this is useless without one.

Update since I posted: I held at 1.7mg for a further twelve weeks and lost another 4kg slowly, which settles it for me. I was escalating because the number was available, not because I had stopped responding.

22 20JenPlateau, SallyK_inj, CryptoCarl and 19 others
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