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Evidence-based GLP-1 & peptide discussion since 2023
ForumsProgress & Lab Results[PREMIUM] 18-month transformation — 12 month update Page 3

[PREMIUM] 18-month transformation — 12 month update

rick_sfbay Thu, May 30, 2024 at 3:37 PM 30 replies 2,506 viewsPage 3 of 6
Dr.ObesityMed
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May 31, 2024 at 8:15 AM#11
NurseKim_ATL said:
Whatever the answer turns out to be, the method for getting there is the same: state the assumption, do the arithmetic in public, and invite the…

Agreed on the substance. I would put less weight on the timescale, because two months of anything is not enough to distinguish a trend from a wobble.

10 8EndoResFellow, PharmacoVig_BOS, SurmountFan_IN and 7 others
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PeptideSynthNJ
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May 31, 2024 at 7:40 PM#12
fiona_VT said:
Weight is a noisy signal — daily variation of one to two kilograms from glycogen, sodium and gut contents — so a fortnight of flat readings is well…

Thank you for spelling out the reasoning rather than just the conclusion.

11 9NurseAsh_DET, BenResearch_OR, MikeKY_noInsulin and 8 others
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jason_paloalto
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Jun 1, 2024 at 7:05 AM#13
NurseKim_ATL said:
Whatever the answer turns out to be, the method for getting there is the same: state the assumption, do the arithmetic in public, and invite the…

I read this differently. The confidence in this thread is running ahead of the evidence, and I would rather the uncertainty were stated than smoothed over because it is unsatisfying.

12 10mona_PHX, andrew_nyc, Dr.EndoEP and 9 others
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Dr.GutHealth
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Jun 1, 2024 at 6:30 PM#14

The figures, for anyone assembling their own picture. If you are going to change something, change one thing and give it long enough to express itself. Four weeks is the usual minimum for anything pharmacological on this board, and two weeks of data has told you almost nothing.

Last edited: Jun 1, 2024 at 11:30 PM
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mike_mod
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Jun 2, 2024 at 5:55 AM#15

Moderator note: a couple of off-topic posts removed.

Last edited: Jun 2, 2024 at 7:55 AM
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