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ForumsCOA & Analytical TestingLC-MS/MS vs HPLC for peptide analysis — November 2025 Page 11

LC-MS/MS vs HPLC for peptide analysis — November 2025

Dr.SportsMedIN Mon, Jul 22, 2024 at 3:37 PM 51 replies 2,260 viewsPage 11 of 11
claudia_zurich
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Feb 27, 2025 at 8:39 AM#51

Clinical perspective, offered as context rather than as advice. Whatever the answer turns out to be, the method for getting there is the same: state the assumption, do the arithmetic in public, and invite the correction. That is slower than asserting, and it is the only version that survives being wrong.

35 8emma_london, tammy_FL, Dr.LipidDallas and 32 others
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ben_calgary
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Mar 5, 2025 at 10:37 PM#52
claudia_zurich said:
Whatever the answer turns out to be, the method for getting there is the same: state the assumption, do the arithmetic in public, and invite the…

This matches mine closely enough to be worth saying so out loud. I had assumed I was the exception until I read this.

Last edited: Mar 6, 2025 at 4:37 AM
36 9CanadaChris, ZaraB_AL, JakeSmashed95 and 33 others
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wei_SG
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Mar 12, 2025 at 12:31 PM#53
claudia_zurich said:
Whatever the answer turns out to be, the method for getting there is the same: state the assumption, do the arithmetic in public, and invite the…

Adding the part of the answer the thread has not reached. Worth answering the question that was asked rather than the one behind it. The narrow version usually has an answer; the broad version usually does not, and answering the broad one is how a thread stops being useful.

37 10Dr.MetabolicMD, RetaRick_CA, JenPlateau and 34 others
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BethLabQueen
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Mar 19, 2025 at 2:21 AM#54

The figures, for anyone assembling their own picture. If you are going to change something, change one thing and give it long enough to express itself. Four weeks is the usual minimum for anything pharmacological on this board, and two weeks of data has told you almost nothing.

Last edited: Mar 19, 2025 at 3:21 AM
38 11cory_ATX, lori_vegas, Dr.PulmRoch and 35 others
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greg_boulder
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Mar 25, 2025 at 4:07 PM#55

A narrower follow-up, since the general answer is now clear:

How would you tell the difference between that and the alternative explanation?

Last edited: Mar 25, 2025 at 6:07 PM
39 12ben_calgary, patPC_UT, Dr.DermMIA and 36 others
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