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Evidence-based GLP-1 & peptide discussion since 2023
ForumsCOA & Analytical TestingLC-MS/MS vs HPLC for peptide analysis — November 2025 Page 7

LC-MS/MS vs HPLC for peptide analysis — November 2025

Dr.SportsMedIN Mon, Jul 22, 2024 at 3:37 PM 51 replies 2,260 viewsPage 7 of 11
Dr.AddMedPHL
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Oct 16, 2024 at 2:09 PM#31

One thing that is still open after PeptideChemSF’s answer:

Did your prescriber agree with that reading, and if not what was their objection?

Last edited: Oct 16, 2024 at 4:09 PM
23 21FitDadDave, RunnerRach, TrialNerd_Beth and 20 others
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pete_nash
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Oct 23, 2024 at 8:06 AM#32
Dr.SportsMedIN said:
Resolved, and the thing that resolved it was the least interesting suggestion in the thread.

Filing a mild objection. Mild because I might be wrong; an objection because nobody has addressed the case that does not fit. I think the framing smuggles in the conclusion. Ask it the other way round and the obvious answer reverses, which usually means the question is doing the work.

That is the short version; the long version is somebody else's post.

Last edited: Oct 23, 2024 at 2:06 PM
24 22Dr.Martinez, mike_mod, SarahChen_PharmD and 21 others
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Dr.RheumBOS
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Oct 30, 2024 at 1:59 AM#33
Dr.SportsMedIN said:
Resolved, and the thing that resolved it was the least interesting suggestion in the thread.

True, and it depends on a baseline nobody has stated. Without knowing where someone started, the same number can be an excellent result or a disappointing one.

Last edited: Oct 30, 2024 at 7:59 AM
25 23cory_ATX, lori_vegas, Dr.PulmRoch and 22 others
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ben_calgary
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Nov 5, 2024 at 7:48 PM#34
Dr.SportsMedIN said:
Resolved, and the thing that resolved it was the least interesting suggestion in the thread.

Thank you for spelling out the reasoning rather than just the conclusion. Taking it to my next appointment.

26 24JakeSmashed95, NauseaFreeNow, SteveThurs and 23 others
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NurseAsh_DET
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Nov 12, 2024 at 1:34 PM#35

Clinical perspective, offered as context rather than as advice. The useful move here is to separate what is established from what is widely repeated. Those two sets overlap less than the confident tone of most write-ups suggests, and the second set is where nearly all the disagreement on this board comes from.

Last edited: Nov 12, 2024 at 7:34 PM
27 0emily_PDX, Dr.SleepRoch, laura_annarbor and 24 others
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