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Evidence-based GLP-1 & peptide discussion since 2023
ForumsCOA & Analytical TestingHas anyone dealt with moisture content analysis for lyophilized peptides? Page 10

Has anyone dealt with moisture content analysis for lyophilized peptides?

newstart_MO Thu, May 30, 2024 at 8:42 AM 54 replies 2,788 viewsPage 10 of 11
tyler_CSCS
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Apr 18, 2025 at 6:28 PM#46
PharmacoVig_BOS said:
The mechanism and the magnitude are separate questions.

Adding the part of the answer the thread has not reached. There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.

26 24sean_dublin, hannah_MT, Dr.SportsMedIN and 23 others
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newstart_MO
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Apr 30, 2025 at 7:26 AM#47

Closing the loop on my own question.

Resolved, and the thing that resolved it was the least interesting suggestion in the thread. Writing that down for the next person who wants the interesting answer.

Last edited: Apr 30, 2025 at 1:26 PM
27 0LibrarianMeg, bri_stats, pete_manc_UK and 24 others
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nick_SD_fit
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Sep 2024
San Diego, CA
May 11, 2025 at 8:17 PM#48

Following on from PharmacoVig_BOS — and this may be the naive question:

What did you change at the same time, and can you separate the two now?

Last edited: May 11, 2025 at 10:17 PM
28 1EndoResFellow, PharmacoVig_BOS, SurmountFan_IN and 25 others
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SandraNC_45
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Charlotte, NC
May 23, 2025 at 9:02 AM#49
newstart_MO said:
Resolved, and the thing that resolved it was the least interesting suggestion in the thread.

Pushing back on newstart_MO here. I think the framing smuggles in the conclusion. Ask it the other way round and the obvious answer reverses, which usually means the question is doing the work.

I would rather be corrected than agreed with, if it comes to it.

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mona_PHX
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Jun 3, 2025 at 9:40 PM#50
newstart_MO said:
Resolved, and the thing that resolved it was the least interesting suggestion in the thread.

Correct, and worth adding that it is reversible. Nothing being described here is a one-way door, which changes how cautious it is reasonable to be.

1 24MariaRD
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