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Evidence-based GLP-1 & peptide discussion since 2023
ForumsNutrition & SupplementationMeal prepping when you have zero appetite is so weird — what worked for you? Page 3

Meal prepping when you have zero appetite is so weird — what worked for you?

dave_SLC Thu, Sep 18, 2025 at 11:57 AM 51 replies 1,950 viewsPage 3 of 11
MikeFit_NJ
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Sep 19, 2025 at 5:57 AM#11
NurseAsh_DET said:
Phantom hunger vs real hunger on food noise: learning to distinguish between the two has been a revelation.

The GLP-1 and alcohol use disorder connection, relevant to food noise: observational data from Scandinavian registries shows reduced alcohol-related hospitalizations in GLP-1 agonist users[1].

The mechanism is plausible: GLP-1R is expressed in the mesolimbic reward pathway (VTA, nucleus accumbens). Agonism at these receptors may reduce the reinforcing properties of alcohol, similar to the reduction in "food noise."

RCTs for GLP-1 agonists in AUD are now underway. If positive, this would be a paradigm-shifting repurposing of existing medications.

References:
[1] Wang W, et al. Nat Med. 2024;30:574-584.
Last edited: Sep 19, 2025 at 8:57 AM
40 13LeilaHI, marcus_mpls, DeniseRN_TPA and 37 others
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emma_london
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Sep 19, 2025 at 3:51 PM#12
JennaRN said:
Alcohol relationship change with food noise: I used to drink 2 glasses of wine most nights.

Genuinely useful, thank you. I had the facts and not the framework. Sending this to two other people who asked me the same thing last week.

41 14mike.trainer_LA, sarah_nash92, FitDadDave and 38 others
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SkepticalSean
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Maine
Sep 20, 2025 at 1:45 AM#13
NurseAsh_DET said:
Phantom hunger vs real hunger on food noise: learning to distinguish between the two has been a revelation.

I do not accept the framing. The question has been narrowed to the version that has a tidy answer, and the part that was dropped is the part the OP actually asked about.

Last edited: Sep 20, 2025 at 5:45 AM
42 15emma_london, tammy_FL, Dr.LipidDallas and 39 others
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PeptideChemSF
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Sep 20, 2025 at 11:40 AM#14

One concrete data point for the thread. Worth stating the units and the reference range whenever you post a number here. A large fraction of the apparent disagreement in these threads is two people using different units and both being right.

Happy to go further on any of that.

Last edited: Sep 20, 2025 at 3:40 PM
43 16ricardo_MIA, BrianDallas92, labquiet_amy and 40 others
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mike_mod
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Sep 20, 2025 at 9:35 PM#15

Moderator note: a couple of off-topic posts removed. Carry on.

44 17PurityPaulOR, MaxMetOK, MounjBrad and 41 others
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