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Evidence-based GLP-1 & peptide discussion since 2023
ForumsOff-TopicHas anyone dealt with books that changed your relationship with food? Page 3

Has anyone dealt with books that changed your relationship with food?

Dr.GastroMayo Thu, Mar 19, 2026 at 2:27 PM 11 replies 820 viewsPage 3 of 3
InsuranceTom
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Mar 23, 2026 at 11:03 AM#11
TinaHashiRN said:
"Food aversion" side effect of food noise that I wasn't prepared for: I used to LOVE cooking and trying new restaurants.
TinaHashiRN said:
...regarding food noise mechanism of action...

To build on this — the mechanism is more complex than "it makes you less hungry." GLP-1 agonists:

  1. Activate hypothalamic satiety centers (appetite reduction)
  2. Delay gastric emptying (prolonged fullness)
  3. Potentiate glucose-dependent insulin secretion
  4. Suppress glucagon secretion
  5. Modulate reward pathway dopaminergic signaling
  6. Reduce hepatic lipogenesis
  7. Have direct cardiovascular protective effects

It's a multi-target drug with systemic metabolic effects. Understanding the mechanism helps us predict and manage side effects.

13 11lisa_labSD, adam_van, Dr.SurgeonPGH and 10 others
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cory_ATX
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Jul 2024
Austin, TX
Mar 24, 2026 at 10:58 AM#12
cory_ATX said:
Rebound hunger after missed dose of food noise: I missed my injection by 3 days due to a shipping delay and the hunger came ROARING back.

This is exactly what I could not find anywhere else.

14 12andrew_nyc, Dr.EndoEP, GraceAZ_72 and 11 others
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CryptoCarl
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Arizona
Mar 25, 2026 at 10:53 AM#13
TinaHashiRN said:
"Food aversion" side effect of food noise that I wasn't prepared for: I used to LOVE cooking and trying new restaurants.

Pushing back on TinaHashiRN here. Pushing back on the consensus forming here. Consistency is not the same as correctness, and a board that agrees with itself quickly is usually agreeing with the first person who sounded certain.

15 13AussieAnna, BethLabQueen, ChrisMacros and 12 others
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bri_stats
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Seattle, WA
Mar 26, 2026 at 10:47 AM#14

Adding the numbers, since they settle part of this. Say what you would expect to see if you were wrong, before you look. It is a small discipline and it changes what you notice.

Last edited: Mar 26, 2026 at 2:47 PM
16 14JessicaM_2024, TomFromTexas, mike.trainer_LA and 13 others
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mike_mod
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Mar 27, 2026 at 10:41 AM#15

Moderator note: the sourcing question belongs in the vendor section and has been split out. No action needed from anybody.

17 15PurityPaulOR, MaxMetOK, MounjBrad and 14 others
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