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Evidence-based GLP-1 & peptide discussion since 2023
ForumsOff-TopicGLP-1 memes thread — what worked for you? Page 3

GLP-1 memes thread — what worked for you?

Dr.EndoIndy Fri, Jan 9, 2026 at 5:49 PM 46 replies 1,782 viewsPage 3 of 10
Dr.KarenChen
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Jan 12, 2026 at 1:54 PM#11
Dr.PathRoch said:
Neuroscience perspective on food noise: GLP-1 receptors are expressed throughout the CNS, with high density in the hypothalamic arcuate nucleus, area…

"Food aversion" side effect of food noise that I wasn't prepared for: I used to LOVE cooking and trying new restaurants. Now certain foods — especially red meat — literally repulse me.

It's not just reduced appetite; it's an active disgust response. My therapist says this is common and likely related to the reward pathway modulation. It's mostly a positive change, but I do miss enjoying food the way I used to.

39 12julia.endo, JessicaM_2024, TomFromTexas and 36 others
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raj_cambridge
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Jan 13, 2026 at 1:39 PM#12
Admin said:
The GLP-1 and alcohol use disorder connection, relevant to food noise: observational data from Scandinavian registries shows reduced alcohol-related…

That reframing is the part I needed.

Last edited: Jan 13, 2026 at 2:39 PM
40 13DoseLogDan, SleepFixSam, PurityPaulOR and 37 others
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PedsEndoPhilly
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Jan 14, 2026 at 1:23 PM#13
Dr.PathRoch said:
Neuroscience perspective on food noise: GLP-1 receptors are expressed throughout the CNS, with high density in the hypothalamic arcuate nucleus, area…

I read this differently from Dr.PathRoch, on substance rather than tone. I think the framing smuggles in the conclusion. Ask it the other way round and the obvious answer reverses, which usually means the question is doing the work.

Last edited: Jan 14, 2026 at 6:23 PM
41 14jason_paloalto, Dr.LeslieOBGYN, MikeNYC_runner and 38 others
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BiostatsBrad
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Jan 15, 2026 at 1:07 PM#14

One concrete data point for the thread. One habit that pays for itself: post the method alongside the number. A figure without its method cannot be checked, and an unchecked figure is how this community accumulates folklore.

42 15james_edin, FranDenver, Dr.BariatricHTX and 39 others
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mike_mod
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Jan 16, 2026 at 12:50 PM#15

Moderator note: two posts asking for a source have been merged into one. Please search the thread before asking again. Tagging this one for the weekly digest.

43 16PurityPaulOR, MaxMetOK, MounjBrad and 40 others
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