Adding the clinical framing, because it changes how the question reads. Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then measure again under the same conditions.

DanielChem_CHI said:

Say what you would expect to see if you were wrong, before you look.

Genuinely useful, thank you. I had the facts and not the framework.

Clinical perspective, offered as context rather than as advice. The mechanism and the magnitude are separate questions. Agreeing that something happens says nothing about whether it happens enough to act on.

Dr.BariatricHTX said:

The mechanism and the magnitude are separate questions.

Second this.

Moderator note: the sourcing question belongs in the vendor section and has been split out. Carry on.