Dr.NephBHM_UK said:

Anti-inflammatory mechanisms of GLP-1 agonists and cardiovascular risk: beyond weight loss, GLP-1R activation directly suppresses NF-κB signaling,…

Same experience, arrived at from the opposite direction.

anders_CPH said:

I'm 67 years old and want to share my perspective on cardiovascular risk as an older member of this community.

Continuous metabolic monitoring dashboard for cardiovascular risk — I track everything in a spreadsheet and here's the month-over-month trend for my key markers:

Weight: consistent downtrend, -1.6 lbs/week average
Fasting glucose (finger stick): stable at 85 mg/dL
Blood pressure (home): 116/75 average
Resting heart rate: 65 bpm (down from 81)
Waist circumference: down 15 inches total

The resting heart rate improvement correlates with cardiovascular fitness gains. Everything is moving in the right direction.

anders_CPH said:

I'm 67 years old and want to share my perspective on cardiovascular risk as an older member of this community.

Positive "side effect" of cardiovascular risk: my blood pressure dropped so much that I'm now off metoprolol entirely! My cardiologist is thrilled.

If you're on BP meds and losing weight on a GLP-1, monitor your BP at home regularly. Hypotension symptoms (dizziness, lightheadedness when standing) mean your BP meds may need reduction. Don't wait for your next scheduled appointment — call your doctor.

anders_CPH said:

I'm 67 years old and want to share my perspective on cardiovascular risk as an older member of this community.

Bookmarking. The distinction being drawn above is the one nobody else makes. Sending this to two other people who asked me the same thing last week.

Moderator note: reminder that nothing in this thread is medical advice, and that clinical claims need a source.