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Evidence-based GLP-1 & peptide discussion since 2023
ForumsOff-TopicNon-scale victories thread — anyone have experience? Page 4

Non-scale victories thread — anyone have experience?

greg_boulder Wed, Jun 26, 2024 at 8:05 AM 17 replies 2,242 viewsPage 4 of 4
BethLabQueen
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Jul 7, 2024 at 1:53 PM#16
Dr.NephBHM_UK said:
Central vs peripheral GLP-1R signaling in food noise: elegant studies using brain-penetrant vs peripherally-restricted GLP-1 agonists show that ~80%…

Can confirm. Same sequence, different timescale.

24 24maya_sedona, stefan_berlin, Dr.EM_Chicago and 21 others
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hans_munich
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Jul 8, 2024 at 7:34 PM#17

Adding the clinical framing, because it changes how the question reads. Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then measure again under the same conditions.

23 23alex_tucson, kevin_tulsa, Dr.PainCLE and 20 others
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lori_vegas
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Jul 10, 2024 at 1:15 AM#18
hans_munich said:
Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then…

Adding a me-too, because a thread of one person's experience is not much use.

22 22oliver_london, tane_welly, Dr.PathRoch and 19 others
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tommy_boulder
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Jul 11, 2024 at 6:55 AM#19
hans_munich said:
Order of operations matters more than any single choice here: establish a baseline, change one thing, wait long enough for it to express itself, then…

There is a second half to this that has not been said yet. If two explanations both fit, the useful question is which one predicts something the other does not. That is answerable; arguing about which sounds more plausible is not.

21 21dan_philly, MeganSA_TX, LarryQC_SD and 18 others
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mike_mod
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Jul 12, 2024 at 12:35 PM#20

Moderator note: a couple of off-topic posts removed.

49 24PurityPaulOR, MaxMetOK, MounjBrad and 46 others
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