DataDave said:

Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a…

Agreed, and one caution: a single measurement is not a measurement. Anything that moves day to day needs a trend before it means anything at all.

That is the short version; the long version is somebody else's post.

DataDave said:

Give anything pharmacological four weeks before you judge it, and give anything measured weekly a four-point rolling average before you call it a…

That reframing is the part I needed.

From the other side of the consultation, briefly. The mechanism and the magnitude are separate questions. Agreeing that something happens says nothing about whether it happens enough to act on.

pat_auckland said:

The mechanism and the magnitude are separate questions.

Adding a me-too, because a thread of one person's experience is not much use. I had assumed I was the exception until I read this.

pat_auckland said:

The mechanism and the magnitude are separate questions.

Adding the part of the answer the thread has not reached. There is a difference between no evidence and evidence of no effect, and this subject is one where the two get swapped freely in both directions.