🍪 CompoundTalk uses cookies to improve your experience, analyze traffic, and personalize content. By continuing to use this site, you agree to our Cookie Policy.
Evidence-based GLP-1 & peptide discussion since 2023
ForumsExercise & Body CompositionCreatine kinase elevations on GLP-1 — what worked for you? Page 5

Creatine kinase elevations on GLP-1 — what worked for you?

A1cHero_PHX Thu, Apr 2, 2026 at 5:38 AM 37 replies 1,327 viewsPage 5 of 8
JenMemphis
Member
267
1,234
Jan 2025
Memphis, TN
Apr 4, 2026 at 6:09 AM#21
Dr.PulmRoch said:
DEXA scan update relevant to lean mass: Scanned at months 0, 6, and 12.

Sharing my comprehensive lab data relevant to lean mass:

BiomarkerBaselineMonth 3Month 6Month 9
Weight (lbs)269264239219
A1C (%)7.96.95.85.6
hsCRP (mg/L)9.05.02.51.5
Triglycerides249189129119

Protocol: Tirzepatide 10mg/wk, resistance training 5x/week, protein 1.5g/kg/day.

The improvements in lean mass are clearly reflected in these numbers. The inflammatory marker reduction (hsCRP) is particularly striking.

47 20MikeKY_noInsulin, Dr.RaviCardio, jennifer_SEA and 44 others
Reply Quote Save Share Report
SurmountFan_IN
Member
789
3,456
May 2024
Indianapolis, IN
Apr 4, 2026 at 6:49 PM#22
Dr.PulmRoch said:
DEXA scan update relevant to lean mass: Scanned at months 0, 6, and 12.

Regarding lean mass: I accidentally injected my dose intramuscularly instead of subcutaneously last week (went in at wrong angle, too deep). Called my pharmacist — they said it's not dangerous but may absorb faster, potentially causing more GI effects.

Sure enough, had worse nausea that day. Lesson learned: pinch the skin properly and use the right needle length for your body composition.

48 21AttorneyGrant, DebRD_ATL, KristenIndy and 45 others
Reply Quote Save Share Report
quinn_sf
Member
489
2,123
Jun 2024
San Francisco, CA
Apr 5, 2026 at 7:28 AM#23
Dr.PulmRoch said:
DEXA scan update relevant to lean mass: Scanned at months 0, 6, and 12.

Genuinely useful, thank you. I had the facts and not the framework. Printing the relevant bit and taking it with me.

Last edited: Apr 5, 2026 at 1:28 PM
49 22mona_PHX, andrew_nyc, Dr.EndoEP and 46 others
Reply Quote Save Share Report

Janoshik Analytical — Independent Testing

Trusted third-party HPLC & mass spectrometry analysis. Verify peptide purity with the lab the community relies on. Independent. Accurate. Transparent.

Verify Your Peptides

GL Biochem (Shanghai) Ltd. — Direct Manufacturer

Est. 1998. The synthesis house behind the vials you send for testing. ISO 9001 and cGMP certified, 1,500+ staff, batch-specific COA with every order.

Browse GL Biochem
Dr.ObesityLA
VIP Member
3,567
19,876
Dec 2023
Los Angeles, CA
Apr 5, 2026 at 8:07 PM#24

Clinical perspective, offered as context rather than as advice. Worth answering the question that was asked rather than the one behind it. The narrow version usually has an answer; the broad version usually does not, and answering the broad one is how a thread stops being useful.

50 23chris_chi24, tampaLisa73, KarenAZ_mom and 47 others
Reply Quote Save Share Report
raj_cambridge
Member
489
2,123
Jun 2024
Cambridge, MA
Apr 6, 2026 at 8:46 AM#25
Dr.ObesityLA said:
Worth answering the question that was asked rather than the one behind it.

Second this. The detail I would add is minor and it is already implied above.

1 24RickReta_CO
Reply Quote Save Share Report

Similar Threads

Resistance training prevents 73% lean mass loss on semaglutide — RCT review11 replies
DEXA scan longitudinal data — 12 months on GLP-1 + lifting18 replies
Zone 2 cardio + GLP-1: synergistic metabolic benefits — evidence18 replies
Creatine kinase elevations on GLP-1 — exercise-induced or concerning?14 replies
Body recomposition protocol: GLP-1 + progressive overload + high protein8 replies
ForumsNewTrendingMembersAccount

Log In

Forgot password?
No account? Register