newstart_MO said:There is also a quality change that the scan cannot see.
This answered a question I did not know how to ask. Printing the relevant bit and taking it with me.
From the other side of the consultation, briefly.
Sharing my comprehensive lab data relevant to lean mass:
| Biomarker | Baseline | Month 3 | Month 6 | Month 9 |
|---|---|---|---|---|
| Weight (lbs) | 273 | 238 | 223 | 213 |
| A1C (%) | 7.8 | 6.3 | 6.2 | 5.5 |
| hsCRP (mg/L) | 8.0 | 4.0 | 2.5 | 0.9 |
| Triglycerides | 223 | 183 | 133 | 103 |
Protocol: Tirzepatide 10mg/wk, resistance training 5x/week, protein 1.5g/kg/day.
The improvements in lean mass are clearly reflected in these numbers. The inflammatory marker reduction (hsCRP) is particularly striking.
KevinCompounds said:Dr.PeteFamMed said: ...the muscle loss concern with lean mass...
OMG yes. lean mass + resistance training is the combo. Can confirm.
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Browse GL BiochemPedsEndoPhilly said:The intervention that works is boring and well evidenced: resistance training two to three times a week at a genuine effort, protein at 1.4 to 2.0…
Regarding lean mass: I accidentally injected my dose intramuscularly instead of subcutaneously last week (went in at wrong angle, too deep). Called my pharmacist — they said it's not dangerous but may absorb faster, potentially causing more GI effects.
Sure enough, had worse nausea that day. Lesson learned: pinch the skin properly and use the right needle length for your body composition.